3-cyanphenylboronic acid pinacol ester - Names and Identifiers
Name | 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile
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Synonyms | 3-cyanphenylboronic acid pinacol ester 3-CYANOPHENYLBORONIC ACID, PINACOL ESTER 3-Cyanobenzeneboronic acid, pinacol ester 3-(tetraMethyl-1,3,2-dioxaborolan-2-yl)benzonitrile 3-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)BENZONITRILE 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile 3-(4,4,5,5-tetraMethyl-1,3,2-dioxoborolan-2-yl)-benzonitrile 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrilele 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile, 2-(3-Cyanophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
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CAS | 214360-46-0
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InChI | InChI=1/C13H16BNO2/c1-12(2)13(3,4)17-14(16-12)11-7-5-6-10(8-11)9-15/h5-8H,1-4H3 |
3-cyanphenylboronic acid pinacol ester - Physico-chemical Properties
Molecular Formula | C13H16BNO2
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Molar Mass | 229.08 |
Density | 1.06±0.1 g/cm3(Predicted) |
Melting Point | 78-82 °C (lit.) |
Boling Point | 341.0±25.0 °C(Predicted) |
Flash Point | 160°C |
Vapor Presure | 8.28E-05mmHg at 25°C |
Appearance | Solid |
Color | White |
Storage Condition | Keep in dark place,Sealed in dry,Room Temperature |
Refractive Index | 1.507 |
MDL | MFCD03789262 |
3-cyanphenylboronic acid pinacol ester - Risk and Safety
Hazard Symbols | Xi - Irritant
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Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin.
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Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36 - Wear suitable protective clothing.
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WGK Germany | 3 |
HS Code | 29319090 |
3-cyanphenylboronic acid pinacol ester - Introduction
3-(4,4, 5,5-tetramethyl-1, 3,2-dioxaborolan-2-yl) benzontril (3-(4,4, 5,5-tetramethyl-1, 3,2-dioxaborolan-2-yl) benzontril) is an organic compound. The following is a brief description of some of its properties, uses, manufacturing methods and safety information:
Nature:
-Appearance: Colorless solid
-Molecular formula: C16H19BN2O2
-Molecular weight: 284.24g/mol
-Melting point: 65-67 ° C
-Boiling point: 423.4 ° C
-Solubility: Soluble in some organic solvents, such as acetone, dimethyl sulfoxide and chlorinated methane
Use:
- 3-(4,4, 5,5-tetramethyl-1, 3,2-dioxaborolan-2-yl)benzonitril can be used for coupling reactions in organic synthesis, such as Suzuki reaction and stile reaction. It can react with aromatic compounds or alkyl halides to form new compounds and help build complex organic molecular structures.
-It can also be used in areas such as drug development, materials science and medical chemistry.
Method:
- 3-(4,4, 5,5-tetramethyl-1, 3,2-dioxaborolan-2-yl)benzonitril can be synthesized by chemical reaction through intermediates such as Phenylboronic acid. The specific synthesis method can be the reaction of Phenylboronic acid with hydrocyanic acid or cyanide, and then the reaction with pinacol ester to generate the target compound.
Safety Information:
- 3-(4,4, 5,5-tetramethyl-1, 3,2-dioxaborolan-2-yl)benzonitril has no obvious harm to the general human body under normal operating conditions, but it still needs to be used with caution.
-Avoid inhalation, ingestion and contact with skin or eyes during operation.
-Appropriate laboratory practices and personal protective measures, such as gloves and protective glasses, must be taken during handling.
-Appropriate storage and disposal of waste, complying with relevant safety regulations and laws and regulations.
Please note that for detailed information on specific applications or areas of study, it is recommended to consult the relevant safety data sheets and literature, or to seek the guidance of a professional chemist.
Last Update:2024-04-09 15:17:55